Cerebral hemodynamics are frequently impaired in a wide range of neurological diseases, including traumatic brain injury and stroke.
Continuous real-time data provides critical insight into embolic activity and blood flow, enabling immediate treatment decisions.
Advanced algorithms focused on mean velocity accuracy
Extended monitoring with autonomous signal reacquisition upon patient movement
Easy access to velocity trends over a 14-day period
Monitor and interpret exams from anywhere
Vasospasm is a pathological, diffuse, and long-lasting narrowing of a vessel lumen that can occur after subarachnoid hemorrhage (SAH).
Occurring between 4 and 15 days after initial hemorrhage, vasospasm requires emergency detection and treatment.
Detection of vasospasm is critical but difficult as only 20-30% of cases present with notable clinical deficits.1 As the only bedside technology capable of monitoring, TCD is essential in the early identification of vasospasm after subarachnoid hemorrhage (SAH). TCD use is a guidelines-supported method for the detection of vasospasm with SEN and SPE of 91% and 71%, respectively.2
Advanced algorithms focused on mean velocity accuracy
Customize protocols based on personal exam preferences
Easy access to velocity trends over a 14-day period
Monitor and interpret exams from anywhere
Kumar G, Shahripour RB, Harrigan MR. Vasospasm on transcranial Doppler is predictive of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: A systematic review and meta-analysis. J Neurosurg. 2016 May;124(5):1257-64.
Esmaeeli, S.; Mcvey, C.; Brenes Bastos, A.; Wang, J.; Gomez-Paz, S.; Hanafy, K.; Vasileios Arsenios, L.; Ogilvy, C.; Thomas, A.; Shaefi, S.; Fehnel, C.; Nozari, A. Robotically Assisted Transcranial Doppler With Artificial Intelligence For Assessment Of Cerebral Vasospasm After Subarachnoid Hemorrhage. Journal of NeuroCritical Care. June 19, 2020.
Chugh C, Agarwal H. Cerebral vasospasm and delayed cerebral ischemia: Review of literature and the management approach. Neurol India. Jan-Feb 2019;67(1):185-200.
Connolly, E. S., Rabinstein, A. A., Carhuapoma, J. R., Derdeyn, C. P., Dion, J., Higashida, R. T., Hoh, B. L., Kirkness, C. J., Naidech, A. M., Ogilvy, C. S., Patel, A. B., Thompson, B. G., & Vespa, P. (2012). Guidelines for the management of aneurysmal subarachnoid hemorrhage: A guideline for healthcare professionals from the american heart association/american stroke association. Stroke. 43(6), 1711–1737.
SCD is a genetic disorder in which individuals produce only abnormal hemoglobin, the molecule in red blood cells that delivers oxygen to the body. Under conditions of stress, this hemoglobin distorts the shape of red blood cells and leads to irreversible sickling.
Sickled cells can occlude the microvasculature which results in the wide range of clinical symptoms seen in SCD. Over time, repeated episodes of sickling in the vessels of the brain result in scarring and progressive narrowing that can lead to stroke.
Without treatment, 11% of children with sickle cell disease will have an ischemic stroke by 20 years of age. Transcranial Doppler (TCD) is used as a screening test to prevent this complication in the sickle cell population. A finding of elevated velocities requires further monitoring or transfusion intervention.5 TCD screening is recommended for SCD patients to begin at 24 months of age and should be repeated every 6-12 months during early childhood.6
Adams R. J. (2005). TCD in sickle cell disease: an important and useful test. Pediatric radiology, 35(3), 229–234.
Zétola V.F. (2012) Role of TCD in sickle cell disease: A review. Perspectives in Medicine, 1(1-12), 265-268.
ECMO is a form of cardiopulmonary life support where blood is circulated outside the body and infused with oxygen before being recirculated back into the body.
The automated NovaGuide can be used to assess cerebral blood flow velocity for extended periods of time while a patient is receiving ECMO support.
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