A shunt is an abnormal communication between the right and left sides of the heart or between the systemic and pulmonary vessels, allowing blood to flow directly from one circulatory system to the other. A right-to-left shunt (RLS) allows deoxygenated systemic venous blood to bypass the lungs and return to the body.
Providing insight into the underlying causes of a stroke, enabling more informed treatment decisions.
Simple assessment of bubble showers with regions of interest automatically identified
Quickly lock onto cerebrovascular signals in less than two minutes
Record bubbles at rest and during Valsalva in 60 second segments
View and interpret exams from anywhere
A PFO is a hole between the left and right atria of the heart
A PFO is the most common source of RLS and has been shown to have a higher prevalence in stroke patients. A PFO closure significantly reduces the rate of recurrent stroke.
A TCD bubble study is non-invasive and has 96% sensitivity for RLS detection.2 Understanding the underlying cause of a stroke allows physicians to make more informed decisions, ultimately leading to better patient management.
NovaGuide Intelligent Ultrasound compared to standard of care TTE for RLS detection
shunt detection rate
63.6% with NovaGuide, 20.9% with TTE
detection of intervenable shunts
27% with NovaGuide, 10% with TTE
Read the full results from this groundbreaking studydownload the results
Katsanos, A. H., Psaltopoulou, T., Sergentanis, T. N., Frogoudaki, A., Vrettou, A. R., Ikonomidis, I., Tsivgoulis, G. (2016). Transcranial Doppler versus transthoracic echocardiography for the detection of patent foramen ovale in patients with cryptogenic cerebral ischemia: A systematic review and diagnostic test accuracy meta-analysis. Annals of Neurology. 2016 Apr;79(4):625-35.
Tobe J, Bogiatzi C, Munoz C, Tamayo A, Spence JD. Transcranial Doppler is Complementary to Echocardiography for Detection and Risk Stratification of Patent. The Canadian journal of Cardiology, 2016 Aug;32(8):986.e9-986.e16.
Rubin, M., Shah, R., et al. Novel Robotic-Assisted Transcranial Doppler versus Transthoracic Echocardiography to Detect Right-to-Left Shunts. New Orleans, LA USA: International Stroke Conference - Late Breaking Abstract.
COVID-19 is a complex disease that can affect multiple organ systems including the brain, heart, and lungs.
Patients with severe COVID-19 pneumonia display high levels of vascular shunting, which is correlated with low lung compliance.4
The robotic nature of NovaGuide enables autonomous monitoring and reduces contact between providers and patients with COVID-19.
NovaGuide detected microbubbles in 83% of mechanically ventilated patients, signaling vascular shunting4READ THE STUDY
Reynolds AS, Lee AG, Renz J, DeSanti, K, Liang J, Powell CA, Ventetuolo CE, Poor HD. Pulmonary Vascular Dilatation Detected by Automated Transcranial Doppler in COVID-19 Pneumonia. American Journal of Respiratory and Critical Care Medicine. August 06, 2020.