Cerebral Blood Flow Velocity Morphology – Large Vessel Occlusion
To collect adequate quality data to develop an algorithmic framework for assessing cerebral vascular occlusions confirmed by standard of care Computer Tomography Angiography (CTA) imaging.
Prospective, multi-center, multi-arm, multi-cohort
Advanced Morphological Analysis of Cerebral Blood Flow for Acute Concussion Diagnosis and Return-To-Play Determination.
To develop and evaluate an analytical platform for quantifying cerebral hemodynamic dysfunction following mild TBI and expand our medical and scientific understanding of these changes.
Prospective, longitudinal, single-center, multi-arm, multi-cohort
Precision Intracranial Bleed Triage and Monitoring
To determine if cerebral hemodynamic dysfunction can be used to rapidly classify traumatic brain injury and determine if the subject(s) are at risk of deteriorating.
Prospective, multi-arm, multi-center, non-invasive
Up to 600
Cerebral Blood Flow Velocity Morphology for Quantification of Intracranial Pressure
To collect high quality cerebral blood flow velocity (CBFV) measurements to develop an algorithmic framework to determine correlation to and estimates of intracranial pressure when measured with invasive monitoring.
Prospective, multi-center, multi cohort, non-invasive
Up to 540
NovaGuide Intelligent Ultrasound Compared to Transthoracic Echocardiography for Detection of Right-to-Left Shunt
To evaluate the shunt detection rate of the NovaGuide Intelligent Ultrasound relative to standard of care diagnostic techniques (TTE, TEE, SOC TCD), and to assess the safety, accuracy and usability of the device.
Prospective, single-arm multi-center, non-significant risk
Up to 150